The DLS technique is particularly powerful for particle size determination in polymer solutions, colloids, and emulsions. However, there are challenges to this technique. Commercial DLS devices face difficulty assessing the size of absorbent and dense samples. The main reason for these problems is the reduced signal-to-noise ratio (SNR) due to the high light exposure volume in conventional DLS techniques. In opaque samples, light cannot penetrate to the desired depth needed for proper detection; therefore, SNR is analytically unacceptable.

In heterogeneous, multiphase, and polymer gel samples, it is crucial to investigate the information about dynamic fluctuations and spatial inhomogeneity. Still, due to the lack of spatial resolution in DLS devices, there are limitations to investigating such samples. Also, measuring particle size distribution is challenging in polydisperse suspensions containing bimodal (or multi-modal).

Addition, Another important issue in DLS measurement is the analysis methods. Each method used in commercial DLS systems has limitations in its assumptions, such as accuracy, speed, and comprehensiveness of analysis.

It is possible to make extremely accurate and repeatable measurements, but knowing the limitations of this technique is essential for obtaining useful data; this is exactly the issue that we work on to overcome the limitation.

Our approach is a novel arrangement of the microscopic system in DLS to increase the spatial resolution. In addition, adding a scanning and multi-angle dynamic light scattering (MADLS) mode together helps to solve the existing problems. In Accuparan, we use the state-of-the-art optical setup that focuses light in a specific area and detects scattered light from the focal point. This method can significantly improve the DLS function.